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Showing posts from December, 2021

10 Best Genomics Stocks to Buy Now - Yahoo Finance

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In this article, we will discuss the 10 best genomics stocks to buy now. You can skip our detailed analysis of these stocks and go directly to the 5 Best Genomics Stocks to Buy Now. Genomics is the branch of biology that deals with the study of human genes. The genome is the complete set of DNA of an organism. Every cell carries copies of nearly three billion DNA base pairs. Organizations operating in the genome industry can be divided into three sub-industries. The first sub-industry is related to Genetic sequencing and analysis. Companies involved in this sub-industry are into sequencing or, in simpler terms, reading and understanding over three billion DNA base pairs. The second sub-industry is Genetic testing and diagnostics, which take the sequencing aspect a step further and use it to pinpoint certain variations in genes and map them to known conditions. The third sub-industry investigates gene editing, which looks into treating or curing diseases that are caused by genetic varia...

PNI in assessing and predicting severity of neonatal sepsis | JIR - Dove Medical Press

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Introduction Sepsis is a life-threatening condition caused by a dysregulated host response to infection and remains a major cause of morbidity and mortality worldwide. 1–3 Neonates are more prone to infections than adults and tend to develop neonatal sepsis due to their immature immune system. 4 Failure to diagnose and manage the bloodstream infection promptly can lead to septic shock, multiple organ failure and death. 5 Therefore, a timely diagnosis of neonatal sepsis is very important. Currently, the gold standard for the diagnosis of neonatal sepsis is blood culture. 6 However, several factors such as inadequate blood volume, antimicrobial exposure and blood contamination pose challenges in confirming the presence of neonatal sepsis. 7 Moreover, the clinical presentation of condition is non-specific. 8 Therefore, biomarkers circulating in the blood may be useful in the early diagnosis of neonatal sepsis. Proper functioning of the body is ensured by adequate nutrition, an...

Compassionate Use Case Study Demonstrating the Potential of - GlobeNewswire

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YONKERS, N.Y., Dec. 20, 2021 (GLOBE NEWSWIRE) -- ContraFect Corporation (Nasdaq: CFRX) , a late clinical-stage biotechnology company focused on the discovery and development of direct lytic agents (DLAs), including lysins and amurin peptides, as new medical modalities for the treatment of life-threatening, antibiotic-resistant infections, announces today the recent publication of a case study report highlighting the potential of its first investigational direct lytic agent, exebacase, to treat methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in a pediatric population. The case report was published in the peer-reviewed Clinical Infectious Diseases , a journal of the Infectious Disease Society of America (IDSA). "These data, although representing a single pediatric patient, provide a compelling case for further evaluation of exebacase in pediatric populations. These findings are especially important given the limited treatment options available to help address the...

Procalcitonin as a Mediator in Sepsis: Are We Reinventing... : Critical Care Medicine - LWW Journals

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Recce Pharmaceuticals encouraged by ongoing Phase I/II clinical trial for burn wound infection treatment, shares up - Proactive Investors USA

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Recce Pharmaceuticals Ltd (ASX:RCE, OTC:RECEF) has received promising data from its ongoing Phase I/II clinical trial for the treatment of burn wound infections with RECCE® 327 (R327), its proprietary synthetic anti-infective. The West Australian Health Department sponsored clinical trial at Fiona Stanley Hospital is assessing the safety and efficacy of R327 in patients with infected burn wounds under Trial ID ACTRN12621000412831. This trial has so far demonstrated a broad-spectrum antibiotic activity from R327 on bacterial burn wound infections, with a visible infection reduction within 24 hours in all patients to date. While the trial is not yet complete, all acute infections treated with R327 were cleared within five days, with chronic infections clearing up within just seven days. Consequently, clinicians were able to reduce the treatment window from the originally planned 14 days, effectively halving the treatment period. This initial success has ...

Osterholm on what we know about omicron — and another pandemic winter - MPR News

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There's still a lot we don't know about the omicron variant of the coronavirus. We know it's been found in at least 16 states now. Minnesota was one of the first to report a case of the variant last week. But researchers are still not sure if it will make people sicker than the delta variant. Michael Osterholm, the director of the University of Minnesota's Center for Infectious Disease Research and Policy, joined host Cathy Wurzer to discuss. He said the evidence so far suggests omicron may be more transmissible than delta, but it might not make people as sick — perhaps due to genetic information that omicron picked up from another virus that causes the common cold in humans. "If a lot of people get [omicron] but it's not causing — on a whole — severe illness across the population, this would be incredibly good news," Osterholm said. In an ideal world, omicron might even outcompete delta, infecting more people with a milder illness and leaving them with ad...

Investigation of association of complement 5 genetic polymor | JIR - Dove Medical Press

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Introduction Sepsis is a heterogeneous disease state arising from systemic inflammatory reactions in response to bacterial and fungal infections. 1 The most common and serious symptom of sepsis is multiple organ dysfunction syndrome, which is associated with high mortality rates worldwide. 2 Despite extensive progress in life support and antibiotic therapy, the mortality rate of sepsis patients worldwide remains as high as 25–30% because of the extreme heterogeneity in disease outcome, such as the heterogeneity in host hereditary susceptibility. 3,4 As the most common type of genetic heterogeneity in humans, single nucleotide polymorphisms (SNPs) in genes encoding inflammatory cytokines, such as NLRP3, MCP-1 and IL-27, are associated with sepsis outcomes. 5–7 Therefore, the identification and quantification of functional genetic variants associated with sepsis will help to exploit new genetic diagnostic and therapeutic approaches, which will improve the prognosis of patients wh...