EBV and the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the agent of COVID-19, are different viruses, but the infected host responses may share important features. Primary EBV infection, infectious mononucleosis, in young adults typically presents with some combination of oropharyngitis, lymphadenopathy, splenomegaly, fever, malaise and fatigue, but it can present with seizures. 1, 2 COVID-19 typically presents with some combination of fever, cough, dyspnea, anosmia, ageusia, headache, nausea, vomiting and diarrhea, but in young adults it may present with seizures, which can be hypothesized to be due to microvascular thrombosis or reversible obstruction from hyperviscosity similar to what happens in the lungs. 3, 4 A 23-year-old male construction worker was brought to hospital on a Sunday morning after having a seizure at church lasting 1–2 min, manifested by staring blankly, jaw clenching and muscle twitching. On arrival, the patient...