ORF Virus Treatment

Covid Live Updates: Layers of Red Tape Burden U.S. Vaccine Donations    The New York Times

COVID-19 Vaccine Reduces Severity, Length, Viral Load for Those Who Still Get Infected    UANews

Virus infections surging in Africa's vulnerable rural areas    Associated Press

Answers About Masks, the Delta Variant and Breakthrough Infections    The New York Times

Inner ear infections: Definition, symptoms, treatment, and more    Medical News Today

Spider-Like Web Mechanism Discovered That Traps and Kills Viruses in the Body    Genetic Engineering & Biotechnology News

COVID-19 vaccine reduces severity, length, viral load for those who still get infected    EurekAlert

COVID-19: Latest Oklahoma case count reveals 737 breakthrough infections as state virus totals rise 36%    Tulsa World

Enochian BioSciences Announces Scientific Presentation of    GlobeNewswire

IgA potentiates NETosis in response to viral infection    pnas.org

Metabolic reprogramming and immune regulation in viral diseases    DocWire News

Covid Live Updates: W.H.O. Officials Warn of Latin America’s Desperation    The New York Times

Post-Covid-19, World Risks Having to Pay Off ‘Immunity Debt’    The Wall Street Journal

Global Viral Vector Manufacturing Market to Reach $1.2 Billion by 2026    PRNewswire

Long COVID-19 could offer lessons for other chronic diseases    The Denver Channel

Detailed simulation of air flow after sneezing to study the transmission of diseases    EurekAlert

Antibiotics use in Africa: Machine learning vs. magic medicine    DW (English)

Emergex to start Phase I trials of T-cell priming vaccine for Dengue    Clinical Trials Arena

Enochian BioSciences Announces Scientific Presentation of Elimination of HBV in Mice with No Evident Toxicity    BioSpace

Know the facts about bovine leukemia virus    Beef Magazine

COVID-19 vaccine reduces severity, length, viral load for those who still get infected    EurekAlert

Answers About Masks, the Delta Variant and Breakthrough Infections    The New York Times

Prevention and Attenuation of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines | NEJM    nejm.org

CHOP researchers discover unique immune response by cells critical to lung health    EurekAlert

Global Virus Network (GVN) Adds Gilead Sciences to GVN Healthcare & Pharma Centers of Excellence Coalition    PRNewswire

Routine bloodborne virus testing integrates feasibly, effectively, sustainably in UK EDs    Healio

Cidara Therapeutics to Present New Analyses for Rezafungin    GlobeNewswire

Spider-Like Web Mechanism Discovered That Traps and Kills Viruses in the Body    Genetic Engineering & Biotechnology News

Atea's AT-527, an Oral Antiviral Drug Candidate, Reduces Viral Replication in Hospitalized Patients with COVID-19 in Phase 2 Interim Analysis    BioSpace

Enochian BioSciences Announces Scientific Presentation of    GlobeNewswire

Virus infections surging in Africa's vulnerable rural areas    Associated Press

Uganda approves use of herbal medicine to treat viral infections    The East African

Kim Jong Un berates North Korean officials for 'crucial' virus lapse    CNBC

RI man diagnosed with rare tick-borne ‘Powassan’ disease    WPRI.com

Virus infections surging in Africa's vulnerable rural areas    ABC News

Patients with SARS-CoV-2 alpha variant do not carry more virus in upper respiratory tract    Healio

Placental Sampling for Understanding Viral Infections - A Simplified Protocol for the COVID-19 Pandemic    DocWire News

Govt approves use of Covidex to treat viral infections    Daily Monitor

Emergex Receives Regulatory Approval for a Phase I Clinical Trial in Dengue of a T-Cell    GlobeNewswire

RI man diagnosed with rare tick-borne ‘Powassan’ disease    WPRI.com

Biden Administration Invests $3 Billion in Developing Antiviral COVID-19 Pill    Verywell Health

WHO releases first-ever global guidance for country validation of viral hepatitis B and C elimination    World Health Organization

Why Experts are So Concerned About the Rise of the Delta Variant    Healthline

Uganda approves use of herbal medicine to treat viral infections    The East African

Australia tightens lockdown amid Delta virus outbreak, vaccine chaos    Reuters

Uganda approves use of herbal medicine to treat viral infections    The East African

A Lack of COVID-19 Genomes Could Prolong the Pandemic Quanta Magazine    Quanta Magazine

Global burden of upper respiratory infections in 204 countries and territories, from 1990 to 2019    The Lancet

Nanobiosensor‐based diagnostic tools in viral infections: Special emphasis on Covid‐19    Wiley

Johannesburg Vulnerable Due to Low Earlier Virus Infections    Bloomberg

Global burden of upper respiratory infections in 204 countries and territories, from 1990 to 2019    The Lancet

What is pharyngitis? Pharyngitis is medical term for a sore throat. Pharyngitis is an inflammation of the pharynx (throat) that results in throat discomfort, pain and/or throat scratchiness; in some individuals it may cause painful swallowing. Sore throat is usually caused by a viral infection and less commonly, a bacterial infection usually by group A streptococci (strep throat). Other causes of sore throat include inflammation due to allergy, toxins, or cancer. Some doctors distinguish pharyngitis from laryngitis and/or tonsillitis, but others do not. Laryngitis is confined to the larynx (voice box) while tonsillitis is inflammation confined to the tonsils. Since it is not unusual for a pharyngitis to spread to adjacent structures like the tonsils or larynx, it is not unreasonable to lump these inflammatory diseases together; however, the symptoms are slightly different for each disease. There are three types of pharyngitis: Non-exudative (does not produce fluids...

A new study in JAMA Internal Medicine found that a sepsis prediction model included as part of Epic's electronic health record may poorly predict sepsis. Using retrospective data, University of Michigan Medical School researchers found that the predictor did not identify two-thirds of sepsis patients.   "In this external validation study, we found the ESM to have poor discrimination and calibration in predicting the onset of sepsis at the hospitalization level," UM researchers wrote.    Epic disputed the study's findings, saying that the authors used a hypothetical approach that did not take into account the analysis and required tuning that needs to occur prior to real-world deployment to get optimal results.   "In their hypothetical configuration, the authors picked a low threshold value that would be appropriate for a rapid response team that wants to cast a wide net to assess more patients," said a statement provided by the company.   "A ...

AUSTIN (KXAN) — Austin doctors are seeing fewer COVID-19 cases, but they're still testing thousands of sick people who think they have the virus. Turns out there are other viruses going around. KXAN checked in with four local doctors to see what's making kids and adults sick. "More adults are coming in with upper respiratory complaints, including rhinitis (colds and allergies)," Dr. Jeffrey Champ with Austin Regional Clinic said. "We are also seeing more anxiety-related complaints as well as patients with COVID-19-related symptoms (fever, cough, muscle ache, headache, fatigue), which are not necessarily indicative of the disease." Champ also said Austin Regional Clinic is testing 1,500 to 1,800 people a week for COVID-19 with a 2% positivity rate. "We're seeing more viral respiratory ailments, colds and some gastrointestinal (stomach) complaints with diarrhea and nausea," pediatrician Dr. Natasha Ahmed said. "We're also seeing ...

Placental Sampling for Understanding Viral Infections - A Simplified Protocol for the COVID-19 Pandemic    DocWire News

Govt approves use of Covidex to treat viral infections    Daily Monitor

Johannesburg Vulnerable Due to Low Earlier Virus Infections    Bloomberg

Virus Outbreak: News and Analysis From June 28    Bloomberg

A Lack of COVID-19 Genomes Could Prolong the Pandemic Quanta Magazine    Quanta Magazine

Nanobiosensor‐based diagnostic tools in viral infections: Special emphasis on Covid‐19    Wiley

Specific lung cell exhibits immune properties and improves respiratory viral disease outcomes    News-Medical.net

A Lack of COVID-19 Genomes Could Prolong the Pandemic Quanta Magazine    Quanta Magazine

Why vaccinations for several diseases are falling sharply in Brazil    National Geographic

Auris Medical to Initiate Market Launch of Bentrio™ Nasal Spray in Germany    GlobeNewswire

Increase in respiratory diseases after mask order dropped    WBRC

Nanobiosensor‐based diagnostic tools in viral infections: Special emphasis on Covid‐19    Wiley

Wayne State receives NSF award to study how airborne viruses navigate through mucus    EurekAlert

Improving Zoonotic Disease Prevention and Livestock Production through Nuclear-derived Techniques Discussed at FAO/IAEA Meeting | IAEA    International Atomic Energy Agency

South Africa tightens restrictions to fight resurgent virus    ABC News

AI Predicts 20,000 Unknown Associations between Viruses and Susceptible Mammalian Species    Genetic Engineering & Biotechnology News

Humans are creating hot spots where bats could transmit zoonotic diseases    National Geographic

Auris Medical to Initiate Market Launch of Bentrio™ Nasal Spray in Germany    GlobeNewswire

Introduction Ebola virus is a member of the Filoviridae family which encompasses six genera: Ebolavirus, Marburgvirus, Striavirus, Thamnovirus, Dianlovirus , and Cuevavirus . 1 The genus Ebolavirus includes six species Zaire ebolavirus (EBOV), Sudan ebolavirus (SUDV), Taï Forest ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus (BDBV), and Bombali ebolavirus . Filoviruses are pleomorphic in shape and possess a lipid envelope. The viral genome is a negative-sense single strand RNA which is approximately 19 kb in size. 1 Since the first outbreak in 1976, EBOV has resurfaced a multitude of times in Africa. Initially, it was responsible for causing small, localized outbreaks until 2013, when the large multinational epidemic was recorded causing 28,646 infections and 11,323 fatalities. 2 A second, large outbreak occurred in the North Kivu province of the Democratic Republic of Congo (DRC) in 2018–2020 totaling 3481 cases and 2299 fatalities. 3,4 There has recently been an o...

Abbreviations AKI acute kidney injury COVID-19 Coronovirus disease 2019 eNOS endothelial nitric oxide synthase RCTs randomised clinical trials SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 SOFA sequential organ failure assessment 1 INTRODUCTION Sepsis is a pathophysiological syndrome characterised by an overwhelming immune response to a bacterial, viral or fungal infection that can lead to multiorgan dysfunction and death (Singer et al.,  2016 ). Sepsis is the leading cause of mortality in intensive care units with an annual global incidence of 49 million cases and 11 million deaths (Rudd et al.,  2020 ). Standard of care treatment for sepsis consists of antibiotics, fluid resuscitation and vasopressors (Rhodes et al.,  2017 ), with continuous renal replacement therapy being increasingly used in critically ill patients (Bellomo et al.,  2021 ). These interventions are mostly aimed towards keeping the patient alive in the expectatio...